Today started, after patch Tuesday, with many machines crashing when one tried to print resulting in the standard “Your PC ran into a problem….” with a Stop Code: APC_INDEX_MISMATCH error, due to win32kfull.sys

UPDATE: Microsoft released updates today, March 16/21 to resolve the problem but you must manually download and install:

Windows 10 emergency updates released to fix printing crashes (bleepingcomputer.com)

UPDATE 2: It seems the first patch further broke some printers resulting in blank pages or missng content. Another ‘out-of-band’ update was released the 18th.

Windows message center | Microsoft Docs

UPDATE 3: Microsoft halts the rollout for the “emergency” patch for the patch for the patch Tuesday update 😦

Microsoft halts rollout of Windows 10 KB5001649 emergency update (bleepingcomputer.com)

With my clients this seemed to happen with any Office or Windows app, even notepad. However Adobe seemed to be OK and oddly if you just right click on any file and choose print, without opening it, it seemed to be OK as well. Many report updating the printer drivers solved the problem, but doing so in my cases “Windows encountered an error”. Uninstalling the printer and reinstalling with the latest drivers did resolve the problem. Also it seems not all printers are problematic. On one system which had multiple printers, the error occurred when printing to any printer, but just reinstalling the Ricoh C2504 printer eliminated the problem for all printers. Google shows Ricoh and Kyocera printers seem to be the most problematic.

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